edited by Dmitry I Gabrilovich (University of South Florida, USA)

This is a second edition of the book, which presents an overview of the most recent findings in the biology of neutrophils. These cells are critically important for protection against bacterial and viral infections and have been implicated in anti-tumor response. In addition, neutrophils represent a unique model for studying fundamental questions of cellular biochemistry and molecular biology. This book provides a detailed description of signal transduction, generation of reactive oxygen, and mechanisms of migration of these cells. It contains unique information on the neutrophil's role in viral infectious diseases and cancer. It also presents the recent advances in attempts to improve neutrophil function and use these cells in the treatment of diseases.

• The Remarkable Neutrophil! Developing a Blueprint for Integrated Cellular Signaling
• The Neutrophil Respiratory Burst Oxidase
• Novel Neutrophil Receptors and Their Signal Transduction
• Mechanisms of Neutrophil Migration
• Neutrophils and Apoptosis
• Regulation of Neutrophil Functions by Long Chain Fatty Acids
• Cytokine Production by Neutrophils
• Neutrophils in Viral Infections
• Polymorphonuclear Neutrophils and Cancer: Ambivalent Role in Host Defense Against Tumor
• Use of Colony-Stimulating Factors for Treatment of Neutropenia and Infectious Diseases
• Neutrophil Transfusion Therapy in G-CSF Era